Novel Approaches in Synthesis of Heterocyclic Compounds: A Focus on 1,2,4-Triazoles and Their Pharmacological Potential

Abstract

Introduction: The synthesis of heterocyclic compounds, particularly 1,2,4-triazoles, has seen remarkable advancements owing to their significant pharmacological properties. This paper reviews novel approaches in the synthesis of 1,2,4-triazoles, including green chemistry methods, multicomponent reactions, metal-catalyzed reactions, and photocatalytic and electrochemical methods.